Authors: Gemma Margetts, Sotirios Kleidonas, Nawel S. Zaibi, Mohamed S. Zaibi, Kieron D. Edward
Institutions: University of Westminster; daacro GmbH & Co. KG; University of Leicester; Sibelius Limited
Source: BMC Complementary Medicine and Therapies. Published: 12 May 2022. Volume 22, Article number: 131.
Objective: This study tested how sage reduces inflammation in the brain and supports brain chemicals for memory.
Methods: Scientists tested sage extract on human gut and brain barrier cells. They measured inflammation markers, antioxidant effects. They also tested sage across 12 human disease models to see its impact on inflammation and brain-related enzymes.
Results: Sage lowered most inflammation signals in gut cells and reduced key markers in brain barrier cells. It also reduced oxidative stress. Testing showed sage works like natural compounds and drugs that block enzymes decreasing dopamine and serotonin. Lab tests confirmed sage blocks these enzymes, increasing dopamine and serotonin, which improve focus, attention, and working memory.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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